Mario Colombo is on the board of Istituto Sperimentale Italiano Lazzaro Spallanzani and B.F. SpA and Chairman of Istituto Zooprofilattico Sperimentale della Lombardia, Director & Scientific Director at Fondazione Iniziative Zooprofilattiche e Zootecniche and Chairman-Environment Department at Associazione Nazionale Comuni Italiani.

In the past he held the position of Professor at the University of Milan.

Mario Colombo received an undergraduate degree from the University of Milan.