| | Variaz. | Variaz. 5g. | Variaz. 1 gen. | Variaz. 1anno | Variaz. 3anni | Capi. (M$) |
 | NEUROCRINE BIOSCIENCES, INC. | 2.03% | 3.68% | -15.25% | 7.97% | 16.95% | 9 582 |
| | | | | | | |
| REGENERON PHARMACEUTICALS, INC. | 1.25% | 9.06% | 13.89% | 17.65% | 68.28% | 86 608 |
| VERTEX PHARMACEUTICALS | 0.93% | 2.43% | 9.10% | 20.73% | 32.41% | 80 254 |
 | WUXI APPTEC CO., LTD. | -2.44% | -3.08% | -1.85% | -29.93% | 52.64% | 34 784 |
| BIONTECH SE | 1.63% | -5.27% | -17.07% | -26.96% | 113.30% | 29 539 |
 | GENMAB A/S | 0.66% | 0.86% | -11.97% | 4.40% | 91.71% | 24 559 |
| BEIGENE, LTD. | -1.22% | -0.37% | -2.01% | 14.28% | 75.07% | 22 778 |
 | ARGENX SE | -0.35% | 2.70% | -2.18% | 20.64% | 184.15% | 20 719 |
| SAREPTA THERAPEUTICS, INC. | 1.32% | 5.96% | 6.37% | 76.43% | 40.90% | 11 968 |
| LEGEND BIOTECH CORPORATION | 0.46% | 9.54% | -3.41% | 32.69% | --.--% | 8 035 |
| KARUNA THERAPEUTICS, INC. | 0.80% | 2.26% | -7.56% | 43.26% | 152.28% | 6 735 |
| EXELIXIS, INC. | 3.08% | 2.73% | 21.01% | -14.38% | 12.72% | 6 103 |
| ASCENDIS PHARMA A/S | -1.23% | 2.91% | -12.21% | -8.64% | -4.79% | 6 102 |
| INTRA-CELLULAR THERAPIES, INC. | -3.39% | 22.14% | 2.32% | -11.51% | 252.31% | 5 340 |
| HALOZYME THERAPEUTICS, INC. | 2.36% | 10.78% | -32.88% | -4.24% | 112.28% | 5 052 |
 | AKESO, INC. | -2.42% | -1.78% | -6.05% | 109.98% | --.--% | 4 436 |
| | | | | | | |
| | Media | 0.10% | 4.06% | -2.97% | 16.29% | 91.02% | |
| | Media ponderata per Capi. | 0.42% | 3.25% | 2.41% | 11.19% | 73.26% | |
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